Istradefylline CAS NO.155270-99-8

Product Details

Drug or intermediate name: Istradefylline (KW6002)

Itrafylline is a selective adenosine A2A receptor antagonist, which is a new type of antiparkinsonian drugs. Itrafylline is the world's first adenosine A2A receptor antagonist. Adenosine A2A receptor is a type of G protein-coupled receptor (GPCR) and also a kind of adenosine receptor, which is widely distributed in the human body. In the brain, adenosine A2A receptors are mainly distributed in the basal ganglia, and the degeneration or abnormality of the basal ganglia is common in Parkinson's disease. The drug is used in combination with drugs containing levodopa to improve the end-of-dose phenomenon of Parkinson's patients.

CAS Number: 155270-99-8

Molecular formula: C35H49N11O9S2

Compound customization, delivery volume: 100mg 1g 100g 1kg 5kg

Purity: greater than or equal to 98% HPLC

Delivery standard: sample COA, sample purity HPLC NMR

Delivery time: specific communication

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伊曲茶碱是一种选择性腺苷A2A受体拮抗剂，这在抗帕金森药物中属于新类型。伊曲茶碱是全球首个腺甘A2A受体拮抗剂。腺甘A2A受体是一类G蛋白偶联受体(GPCR)，也是腺甘受体的Chemicalbook一种，广泛分布于人体内。在大脑中，腺甘A2A受体主要分布于基底神经节内，而基底神经节的退化或异常常见于帕金森病。该药与含左旋多巴的药品联合使用，用于改善帕金森病人的剂末现象。

分子式:C20H24N4O4